Table 4

Multivariable regression with final eTICI (≥2c) as outcome and First Pass Effect (eTICI 2c after first pass)

	Final eTICI (≥2c)		First pass efficacy (≥2c)
	Or (95% CI)	P-value	Or (95% CI)	P-value
HCG	1.75 (1.21, 2.54)	0.004	1.42 (0.94, 2.14)	0.10
Primary technique		0.72(2)		0.01
SR Classic	Reference		Reference
SR Combination	1.03 (0.70, 1.52)	0.88	1.09 (0.68, 1.73)	0.71
ADAPT	1.19 (0.77, 1.83)	0.43	0.48 (0.28, 0.83)	0.009
Clot location*		0.003(2)		0.18
ICA	Reference		Reference
M1	1.27 (0.99, 1.62)	0.06	1.24 (0.92, 1.67)	0.16
M2	0.64 (0.47, 0.89)	0.008	1.08 (0.77, 1.50)	0.65
Other distal (A1, A2, M3)	0.32 (0.07, 1.42)	0.13	0.12 (0.01, 1.11)	0.06
Extracranial tandem lesions	1.76 (1.20, 2.56)	0.004	1.41 (0.86, 2.34)	0.17
General anesthesia	1.53 (1.08, 2.16)	0.02	1.29 (0.88, 1.90)	0.18
IV tPA	1.08 (0.83, 1.40)	0.56	0.97 (0.73, 1.29)	0.81

*These variables are core lab reported. All other variables are site-reported. All variables in the model were selected a priori by the investigator and forced into the model. No stepwise selection methods were used.
ADAPT, a direct aspiration first pass technique; HCG, high cervical group; IV tPA, intravenous tissue plasminogen activator; SR, stent retriever.