Table 1

Model inputs used in probabilistic sensitivity analysis

Model variableDistributionValue and confidence intervals
% of patients that have thrombectomyBetaDTAS: 83% (62% to 100%)
DTCT: 86% (64% to 100%)
Utility values: mRS 0–6BetamRS 0 (functional independence): 0.93 (0.7 to 1). mRS 1 (functional independence): 0.88 (0.66 to 1). mRS 2 (functional independence): 0.78 (0.59 to 0.98). mRS 3 (disabled): 0.58 (0.44 to 0.73). mRS 4 (disabled): 0.37 (0.28 to 0.46). mRS 5 (disabled): 0.09 (0.07 to 0.11). mRS 6 (death): 0
Patient distributions according to utilities – DTASBetamRS 0 (functional independence): 8% (6% to 10%). mRS 1 (functional independence): 20% (15% to 25%). mRS 2 (functional independence): 15% (11% to 19%). mRS 3 (disabled): 15% (11% to 19%). mRS 4 (disabled): 14% (10% to 17%). mRS 5 (disabled): 7% (5% to 8%). mRS 6 (death): 22% (16% to 27%)
Patient distributions according to utilities – DTCTBetamRS 0 (functional independence): 1% (1% to 2%). mRS 1 (functional independence): 11% (8% to 14%). mRS 2 (functional independence): 15% (11% to 19%). mRS 3 (disabled): 19% (14% to 24%). mRS 4 (disabled): 10% (7% to 12%). mRS 5 (disabled): 10% (7% to 12%). mRS 6 (death): 34% (26% to 43%)
CBCT and angiosuite costGamma€2 000 000 (€1 500 000 to €2 500 000)
CT costGamma0
Costs related to mRS – DTASGammamRS 0 (functional independence): €11 536 (€8652 to €14,420). mRS 1 (functional independence): €16 286 (€12 214 to €20 357). mRS 2 (functional independence): €12 665 (€9 499 to €15 831). mRS 3 (disabled): €13 784 (€10 338 to €17 230). mRS 4 (disabled): €26 315 (€19 736 to €32 894). mRS 5 (disabled): €26 295 (€19 721 to €32 869). mRS 6 (death): €17 250 (€12 937 to €21 562)
Costs related to mRS – DTCTmRS 0 (functional independence): €13 669 (€10 252 to €17 086). mRS 1 (functional independence): €15 951 (€11 963 to €19 938). mRS 2 (functional independence): €19 494 (€14 620 to €24 367). mRS 3 (disabled): €19 074 (€14 306 to €23 843). mRS 4 (disabled): €26 266 (€19 699 to €32 832). mRS 5 (disabled): €31 530 (€23 647 to €39 412). mRS 6 (death): €18 189 (€13 642 to €22 736)

  • €1∼$1.10.

  • CBCT, cone-beam CT; DTAS, direct to angiography suite; DTCT, direct to CT; mRS, modified Rankin Scale.