Patient and aneurysm characteristics (per-protocol analysis)
| Characteristic | Unruptured cohort | Ruptured cohort | ||
| Patient age | 57.3±13.9 years (21–86 years) | 55.9±14.5 years (29–83 years) | ||
| Gender | Males | Females | Males | Females |
| 29 (27.9%) | 75 (72.1%) | 5 (29.4%) | 12 (70.6%) | |
| Number of aneurysms treated by the same PEDV | Single | Multiple | Single | Multiple |
| 97 (93.3%) | 7 (6.7%) | 14 (82.4%) | 3 (17.6%) | |
| Aneurysm location* | ICA para-ophthalmic: 36 (32.4%) | ICA para-ophthalmic: 4 (20.0%) | ||
| ICA PCOM: 23 (20.7%) | MCA: 3 (15.0%) | |||
| ICA cavernous: 16 (14.4%) | PICA: 3 (15.0%) | |||
| Ophthalmic: 14 (12.6%) | ICA PCOM: 2 (10.0%) | |||
| MCA: 6 (5.4%) | Ophthalmic: 2 (10.0%) | |||
| ACOM: 5 (4.5%) | ICA cavernous: 1 (5.0%) | |||
| Basilar: 3 (2.7%) | ICA choroidal: 1 (5.0%) | |||
| PICA: 2 (1.8%) | ICA terminal: 1 (5.0%) | |||
| ICA choroidal: 2 (1.8%) | ACA: 1 (5.0%) | |||
| ICA terminal: 1 (0.9%) | ACOM: 1 (5.0%) | |||
| ACA: 1 (0.9%) | PCA: 1 (5.0%) | |||
| ICA cervical: 1 (0.9%) | ||||
| Vertebral: 1 (0.9%) | ||||
| Anterior or posterior circulation | Anterior: 105 (94.6%) | Posterior: 6 (5.4%) | Anterior: 16 (80.0%) | Posterior: 4 (20.0%) |
| Sidewall/bifurcation | Sidewall: 96 (86.5%) | Bifurcation: 15 (13.5%) | Sidewall: 15 (75.0%) | Bifurcation: 5 (25.0%) |
| Arterial branch originating from aneurysm sac | 27 (24.3%) | 5 (25.0%) | ||
| Hunt and Hess scale | N/A | 1: 7 (41.2%) | ||
| 1 a: 1 (5.9%) | ||||
| 2: 3 (17.6%) | ||||
| 3: 6 (35.3%) | ||||
| Thrombosed aneurysms | Partially thrombosed: 17 (15.3%) | None (0%) | ||
| Shape | Saccular: 103 (92.8%) | Saccular: 16 (80.0%) | ||
| Fusiform: 6 (5.4%) | Fusiform: 1 (5.0%) | |||
| Blister: 2 (1.8%) | Blister: 3 (15.0%) | |||
| Aneurysm type | True aneurysm: 107 (96.4%) | True aneurysm: 18 (90%) | ||
| Pseudo-aneurysm: 4 (3.6%) | Pseudo-aneurysm: 2 (10%) | |||
| Aneurysms with lobular morphology or daughter sac | 37 (33.3%) | 6 (30%) | ||
| Aneurysm measurements (mm or ratio) | ||||
| Neck | 4.8+2.1 (1.2–12) | 3.1+1.7 (1.0–7.2) | ||
| Dome width | 8.2+6.3 (1–37) | 4.4+5.0 (1.5–23.3) | ||
| Height | 8.4+6.2 (1–35.5) | 3.6+3.6 (1.0–16.2) | ||
| Maximum diameter | 9.6+6.7 (1.5–37) | 4.9+4.8 (1.5–23.0) | ||
| Mean dome-to-neck (W/N) | 1.7+1.7 (0.7–14.0) | 1.3+0.6 (0.7–3.2) | ||
| Mean aspect ratio (H/N) | 1.7+1.1 (0.4–6.3) | 1.2+0.6 (0.3–2.5) | ||
| Mean width-to-height (W/H) | 1.0+0.4 (0.4–2.8) | 1.3+0.6 (0.6–3.0) | ||
| Aneurysm class† | ||||
| Small aneurysms | 26 (23.4%) | 12 (60.0%) | ||
| Medium aneurysms | 44 (39.6%) | 6 (30.0%) | ||
| Large aneurysms | 37 (33.3%) | 2 (10.0%) | ||
| Giant aneurysms | 4 (3.6%) | 0 (0.0%) | ||
| Wide-neck aneurysms | 60 (54.1%) | 4 (20.0%) | ||
Data are presented as mean±standard deviation, range or absolute number of cases (relative frequency in %).
Relative frequency for patient gender and number of aneurysms treated by the same PEDV is related to the number of patients (n=104 for unruptured and n=17 for ruptured).
Relative frequency for the remaining data is related to the number of aneurysms (n=111 for unruptured and n=20 for ruptured).
*ACA, anterior cerebral artery (distal to the ACOM); ACOM, anterior communicating artery; ICA, internal carotid artery; MCA, middle cerebral artery; PCA, posterior cerebral artery; PICA, posterior inferior cerebellar artery. NYU ICA anatomical classification used.21
†Aneurysms were classified into small (<5 mm), medium, large (≥10 mm), and giant aneurysms (≥25 mm). Wide-neck aneurysms defined as neck >4 mm.22
N/A, not applicable; PEDV, Pipeline Vantage Embolization Device.