Angiographic and clinical outcomes in patients with AC-LVO treated with DA or combined therapy as first-line device
| Ref | Device | % M1 occlusion | % catheter with ID >0.068 | % with aspiration | % with BGC | After first line | At the end | Median or mean procedural time (min) | % use of rescue therapy | Complications | % mRS 0–2 | % mRS 6 | ||||
| % TICI >2b | % TICI 3 | % FPE | % TICI >2b | % TICI 3 | ENT | sICH | ||||||||||
| Turk 2014 | DA | 74.9% | 0% | 100% | 0% | 41.7%* | NA | NA | 78.5% | 28.5%* | 85.1* | NA | NA | NA | 36.4% | NA |
| DA+SR | 0% | 100% | 0% | 70.1%* | NA | NA | 77.8% | 59.3%* | 51.6* | NA | NA | NA | 50.0% | NA | ||
| Delgado 2015 | DA | 47% | 0% | 100% | 0% | NA | NA | NA | 89% | NA | 50 | 28.9% | 4% | 2% | 56%* | 18% |
| DA+SR | 66% | 0% | 100% | 0% | NA | NA | NA | 84% | NA | 51 | 12.7% | 2% | 13% | 31%* | 29% | |
| Hesse 2017 | DA | 60% | NA | NA | NA | NA | NA | 17% | 73% | 27.5% | 49 | 34% | 11.6% | 7.0% | NA | NA |
| SR | 65% | NA | NA | NA | NA | NA | 14% | 65% | 19% | 62 | 10% | 9.8% | 5.1% | NA | NA | |
| DA+SR | 53% | NA | NA | NA | NA | NA | 26% | 86% | 37.5% | 55 | NA | 6.6% | 9.2% | NA | NA | |
| Nogueira 2018 | DA | 61% | 0% | 100% | NA | 69.8% | NA | NA | 77.3% | NA | 39 | NA | NA | 5.0% | 45.8% | 26.0% |
| DA+SR | 66.3% | 100% | NA | 81.9% | NA | NA | 87.4% | NA | 45 | NA | NA | 3.1% | 45.3% | 19.4% | ||
| Brehm 2019 | DA | 50% | 62.2% | 100% | 0% | NA | NA | NA | 75%* | 22.2% | 55.6 | 30.6% | 12.5% | 4.2% | NA | NA |
| DA+SR | 58.6% | 100% | 0% | NA | NA | NA | 93.5%* | 28.3% | 52.1 | 2% | 3% | 5.2% | NA | NA | ||
*Indicates statistically significant difference.
AC-LVO, anterior circulation large vessel occlusion; BGC, balloon guided catheter; DA, distal aspiration; ENT, embolization in new territory; FPE, first pass effect; ID, inner diameter; mRS, modified Rankin scale; NA, not available; sICH, symptomatic intracranial hemorrhage; SR, stent retriever; TICI, Thrombolysis In Cerebral Infarction.